# Parameters file for the S1-S2 Actors Study (S1) # Mesh Needs to be generated first by Carputils meshname = /code/openCARP-Actors/simulations/Joyce_Sep26_4x4x025mm-input/meshes/4x4x025_mesh/block ############### physical regions ############## num_phys_regions = 2 phys_region[0].name = "Intracellular domain" phys_region[0].ptype = 0 phys_region[0].num_IDs = 1 phys_region[0].ID[0] = 1 phys_region[1].name = "Extracellular domain" phys_region[1].ptype = 1 phys_region[1].num_IDs = 1 phys_region[1].ID[0] = 1 ############### ionic setup ################### num_imp_regions = 1 imp_region[0].im = Shannon ############## stimulus setup ################# num_stim = 2 stimulus[0].name = "S1" stimulus[0].stimtype = 1 stimulus[0].duration = 2. stimulus[0].start = 0. stimulus[0].npls = 1 stimulus[0].x0 = -12.5 #in um stimulus[0].xd = 248.6 #thickness in um stimulus[0].y0 = -12.5 stimulus[0].yd = 248.6 stimulus[0].z0 = 12.5 stimulus[0].zd = 25.0 stimulus[1].name = "Ground" stimulus[1].stimtype = 3 stimulus[1].x0 = -12.5 stimulus[1].xd = 4025.0 stimulus[1].y0 = -12.5 stimulus[1].yd = 4025.0 stimulus[1].z0 = -12.5 stimulus[1].zd = 25.0 ################# Simulation parameters ################# bidomain = 1 tend = 70. spacedt = 1.0 timedt = 1.0 parab_solve = 1 ############# Notes ############# # S1-S2 script params to start with: # S1 min = 1.0e7 # S1 max = 3.0e7 # (Actual S1 threshold = 28,167,114) # Absolute S2 max = 3.0e8 (could go higher if needed, it depends when the solution blows up.) # S1S2_interval_min=185 # S1S2_interval_max=205 (If it is still refractory here, we can extend the range. If it is not, # we can extend it in the other direction by lowering min.) # S1S2_interval_increment=1 # This interval range is subject to change...I have it so that we find 20 data points, # but I don't know what the proper min and max is for this setup yet. # tol = 1 # So far I have tolerance at 1, but because we are working on a much larger scale, we could probably # increase this number quite a bit if needed. # Sample points - 2 in bottom left, 2 in bottom right, 2 close to centre, 4 in top left, 4 in top right. # E.g.: Bottom Left = (2, 2, 0.5), (2, 2, 1.5) # Bottom Right = (8, 8, 0.5), (8, 8, 1.5) # Centre = (3.5, 5, 0.5), (6.5, 5, 1.5) # Top Left = (0, 10, 0.5), (0, 10, 1.5), (0.5, 9.5, 0.25), (0.5, 9.5, 1.75) # Top Right = (10, 10, 0.5), (10, 10, 1.5), (9.5, 9.5, 0.25), (9.5, 9.5, 1.75) # These are somewhat arbitrary, we will need to test these out and see how they go. # Also, it is unlikely that these exact coordinates are vertices. This is okay, however, in the paper, # we should put what the actual coordinates are.